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pentobarbital will minimize the level or impact of terbinafine by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep an eye on.pentobarbital decreases amounts of panobinostat by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Strong CYP3A4 inducers can cut down panobinostat degrees by ~70% and bring abou